publication2011-2015

Publication

Combining suppression of stemness with lineage-specific induction leads to conversion of pluripotent cells into functional neurons

Debasish Halder, Gyeong-Eon Chang, Debojyoti De, Eunji Cheong, Kyeong Kyu Kim,* Injae Shin*

Chem. Biol. 2015, 22, 1512-1520

Synthetic Small Molecules That Induce Neuronal Differentiation in Neuroblastoma and Fibroblast Cells

Debasish Halder,+ Gun-Hee Kim,+ Injae Shin*

Mol. BioSyst. 2015, 11, 2727-2737

Invited, Cover Image

Probing the effect of an inhibitor of an ATPase domain of Hsc70 on clathrin-mediated endocytosis

Hyungseoph J. Cho, Gun-Hee Kim, Seong-Hyun Park, Ji Young Hyun, Nak-Kyoon Kim, Injae Shin*

Mol. BioSyst. 2015, 11, 2763-2769

Invited

O-linked N-acetylglucosamine glycosylation of p65 aggravated the inflammation in both fibroblast-like synoviocytes stimulated by tumor necrosis factor-a and mice with collagen induced arthritis

Han Byeol Kim, Sang-Won Lee, Chin Hee Mun, Ji Young Yoon, Jaeyoung Pai, Injae Shin,* Yong-Beom Park, Soo-Kon Lee, Jin Won Cho

Arthritis Res. Ther. 2015, 17, 248

A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens

Kyung-Hwa Baek, Haiying Zhang, Bo Ryeong Lee, Young-Guen Kwon, Sang-Jun Ha,* Injae Shin*

Sci. Rep. 2015, 5, 17642

Synthetic aminopyrrolic receptors have apoptosis inducing activity

Seong-Hyun Park, Yoon Pyo Choi, Jinhong Park, Andrew Share, Oscar Francesconi, Cristina Nativi, Wan Namkung, Jonathan L. Sessler, Stefano Roelens, Injae Shin*

Chem. Sci. 2015, 6, 7284-7292

Probing Cell-Surface Carbohydrate Binding Proteins with Dual-Modal Glycan-Conjugated Nanoparticles

Sungjin Park,+ Gun-Hee Kim,+ Seong-Hyun Park, Jaeyoung Pai, Dominea Rathwell, Jin-Yeon Park, Young-Sun Kang, Injae Shin*

J. Am. Chem. Soc. 2015, 137, 5961-5968

A small molecule inhibitor of ATPase activity of Hsp70 induces apoptosis and has antitumor activities

Sung-Kyun Ko, Jiyeon Kim, Deuk Chae Na, Sookil Park, Seong-Hyun Park, Ji Young Hyun, Kyung-Hwa Baek, Nam-Doo Kim, Nak-Kyoon Kim, Young Nyun Park, Kiwon Song, Injae Shin*

Chem. Biol. 2015, 22, 391-403

Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells

Sung-Kyun Ko+, Sung Kuk Kim+, Andrew Share, Vincent M. Lynch, Jinhong Park, Wan Namkung, Wim Van Rossom, Nathalie Busschaert, Philip A. Gale*, Jonathan L. Sessler*, Injae Shin*

Nat. Chem. 2014, 6, 885-892

Highlights in Nat. Chem. Biol. (Transporters: Death by ions) and Chem. Biol. (A Dash of Salt to Induce Apoptosis)

Imidazole-based small molecules that promote neurogenesis in pluripotent cells

Gun-Hee Kim, Debasish Halder, Jinhong Park, Wan Namkung, Injae Shin*

Angew. Chem. Int. Ed. 2014, 53, 9271-9274

Selective homocysteine turn-on fluorescent probes and their bioimaging applications

Hye Yeon Lee, Yoon Pyo Choi, Sunkyung Kim, Taejin Yoon, Zhiqian Guo, Songyi Lee, K. M. K. Swamy, Gyoungmi Kim, Jin Yong Lee,* Injae Shin,* Juyoung Yoon*

Chem. Commun. 2014, 50, 6967-6969

Cover Image

Synthesis of a highly Zn2+-selective cyanine-based probe and its use for tracing endogenous zinc ions in cells and organisms

Zhiqian Guo,+ Gun-Hee Kim,+ Juyoung Yoon,* Injae Shin*

Nat. Protoc. 2014, 9, 1245-1254

Recent Progress in the Development of Near-Infrared Fluorescent Probes for Bioimaging Applications

Zhiqian Guo, Sookil Park, Juyoung Yoon,* Injae Shin*

Chem. Soc. Rev. 2014, 43, 16-29

Invited, Cover Image, Selected as top 10% of highly cited papers

Highly Selective Ratiometric Fluorescent Probe for Au3+ and Its Application to Bioimaging

Ji Young Choi,+ Gun-Hee Kim,+ Zhiqian Guo,+ Hye Yeon Lee, K. M. K. Swamy, Jaeyoung Pai, Seunghoon Shin, Injae Shin,* Juyoung Yoon*

Biosens. Bioelectron. 2013, 49, 438-441

Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals

Minjeong Kim, Sung-Kyun Ko, Hyemi Kim, Injae Shin,* Jinsung Tae*

Chem. Commun. 2013, 49, 7959-7961

Carbohydrate chemistry

Injae Shin,* Kwan Soo Kim*

Chem. Soc. Rev. 2013, 42, 4267-4269

Editorial

Carbohydrate microarrays

Sungjin Park, Jeffrey C. Gildersleeve,* Ola Blixt,* Injae Shin*

Chem. Soc. Rev. 2013, 42, 4310-4326

Invited, Cover Image

Dual-labeled glycoclusters: synthesis and their application to monitoring lectin-mediated endocytosis

Xizhe Tian, Kyung-Hwa Baek, Injae Shin*

Mol. BioSyst. 2013, 9, 978-986

Invited

Dual-Targeting Delivery System for Selective Cancer Cell Death and Imaging

Xizhe Tian, Kyung-Hwa Baek, Injae Shin*

Chem. Sci. 2013, 4, 947-956

Cover Image

High-throughput Profiling of Peptide-RNA Interactions Using Peptide Microarrays

Jaeyoung Pai, Taejin Yoon, Nam Doo Kim, Im-Soon Lee, Jaehoon Yu,* Injae Shin*

J. Am. Chem. Soc. 2012, 134, 19287-19296

Analysis of density-dependent binding of glycans by lectins using carbohydrate microarrays

Xizhe Tian, Jaeyoung Pai, Injae Shin*

Chem. Asian J. 2012, 7, 2052-2060

Cover Image

A Cyanine-Based Fluorescent Sensor for Detecting Endogenous Zinc Ions in Live Cells and Organisms

Zhiqian Guo, Gun-Hee Kim, Injae Shin,* Juyoung Yoon*

Biomaterials, 2012, 33, 7818-7827

Cardiosulfa Induces Heart Deformation in Zebrafish Through the AhR-mediated, CYP1A-Independent Pathway

Sung-Kyun Ko, Injae Shin*

ChemBioChem. 2012, 13, 1483-1489

Fluorescent zinc sensor with minimized proton-induced interferences: photophysical mechanism for fluorescence turn-on response and detection of endogenous free zinc ions

Ji Eon Kwon, Sumin Lee, Youngmin You,* Kyung-Hwa Baek, Kei Ohkubo, Jaeheung Cho, Shunichi Fukuzumi,* Injae Shin,* Soo Young Park,* Wonwoo Nam*

Inorg. Chem. 2012, 51, 8760-8774

Cover Image

Recognition and Sensing Various Species Using Boronic Acid Derivatives

Zhiqian Guo, Injae Shin,* Juyoung Yoon*

Chem. Commun. 2012, 48, 5956-5967

Invited

Autophagy-regulating small molecules and their therapeutic applications

Kyung-Hwa Baek, Jihye Park, Injae Shin*

Chem. Soc. Rev. 2012, 41, 3245-3263

Invited, Cover Image

High-Contrast Reversible Fluorescence Photoswitching of Dye-Crosslinked Dendritic Nanoclusters in Living Vertebrates

Yoonkyung Kim,* Hye-youn Jung, Yun Hui Choe, Chaewoon Lee, Sung-Kyun Ko, Soonil Koun, Yohan Choi, Bong Hyun Chung, Byoung Chul Park, Tae-Lin Huh, Injae Shin*, Eunkyoung Kim

Angew. Chem. Int. Ed. 2012, 51, 2878-2882

A Small Molecule That Binds to an ATPase Domain of Hsc70 Promotes Membrane Trafficking of Mutant Cystic Fibrosis Transmembrane Conductance Regulator

Hyungseoph J. Cho, Heon Yung Gee, Kyung-Hwa Baek, Sung-Kyun Ko, Jong-Moon Park, Hookeun Lee, Nam-Doo Kim, Min Goo Lee,* Injae Shin*

J. Am. Chem. Soc. 2011, 133, 20267-20276

Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

Xiaoqiang Chen, Xizhe Tian, Injae Shin,* Juyoung Yoon*

Chem. Soc. Rev. 2011, 40, 4783-4804

Fluorophore-labeled, Peptide-based Glycoclusters: Synthesis, Binding Properties for Lectins and Detection of Carbohydrate-binding Proteins in Cells

Xizhe Tian, Jaeyoung Pai, Kyung-Hwa Baek, Sung-Kyun Ko, Injae Shin*

Chem. Asian J. 2011, 6, 2107-2113

Invited

Zebrafish as a good vertebrate model for molecular imaging using fluorescent probes

Sung-Kyun Ko, Xiaoqiang Chen, Juyoung Yoon,* Injae Shin*

Chem. Soc. Rev. 2011, 40, 2120-2130

Chemical Biology Laboratory

Publication

Combining suppression of stemness with lineage-specific induction leads to conversion of pluripotent cells into functional neurons

Synthetic Small Molecules That Induce Neuronal Differentiation in Neuroblastoma and Fibroblast Cells

Probing the effect of an inhibitor of an ATPase domain of Hsc70 on clathrin-mediated endocytosis

O-linked N-acetylglucosamine glycosylation of p65 aggravated the inflammation in both fibroblast-like synoviocytes stimulated by tumor necrosis factor-a and mice with collagen induced arthritis

A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens

Synthetic aminopyrrolic receptors have apoptosis inducing activity

Probing Cell-Surface Carbohydrate Binding Proteins with Dual-Modal Glycan-Conjugated Nanoparticles

A small molecule inhibitor of ATPase activity of Hsp70 induces apoptosis and has antitumor activities

Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells

Imidazole-based small molecules that promote neurogenesis in pluripotent cells

Selective homocysteine turn-on fluorescent probes and their bioimaging applications

Synthesis of a highly Zn2+-selective cyanine-based probe and its use for tracing endogenous zinc ions in cells and organisms

Recent Progress in the Development of Near-Infrared Fluorescent Probes for Bioimaging Applications

Highly Selective Ratiometric Fluorescent Probe for Au3+ and Its Application to Bioimaging

Rhodamine cyclic hydrazide as a fluorescent probe for the detection of hydroxyl radicals

Carbohydrate chemistry

Carbohydrate microarrays

Dual-labeled glycoclusters: synthesis and their application to monitoring lectin-mediated endocytosis

Dual-Targeting Delivery System for Selective Cancer Cell Death and Imaging

High-throughput Profiling of Peptide-RNA Interactions Using Peptide Microarrays

Analysis of density-dependent binding of glycans by lectins using carbohydrate microarrays

A Cyanine-Based Fluorescent Sensor for Detecting Endogenous Zinc Ions in Live Cells and Organisms

Cardiosulfa Induces Heart Deformation in Zebrafish Through the AhR-mediated, CYP1A-Independent Pathway

Fluorescent zinc sensor with minimized proton-induced interferences: photophysical mechanism for fluorescence turn-on response and detection of endogenous free zinc ions

Recognition and Sensing Various Species Using Boronic Acid Derivatives

Autophagy-regulating small molecules and their therapeutic applications

High-Contrast Reversible Fluorescence Photoswitching of Dye-Crosslinked Dendritic Nanoclusters in Living Vertebrates

A Small Molecule That Binds to an ATPase Domain of Hsc70 Promotes Membrane Trafficking of Mutant Cystic Fibrosis Transmembrane Conductance Regulator

Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

Fluorophore-labeled, Peptide-based Glycoclusters: Synthesis, Binding Properties for Lectins and Detection of Carbohydrate-binding Proteins in Cells

Zebrafish as a good vertebrate model for molecular imaging using fluorescent probes